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广州健仑生物科技有限公司
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恶性疟原虫、间日疟原虫、三日疟原虫、卵形疟原虫检测试剂盒
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美国NovaBios疟原虫检测试剂 疟原虫抗原检测试剂盒
生活史
寄生于人体的4种疟原虫生活史基本相同,需要人和按蚊二个宿主。在人体内先后寄生于肝细胞和红细胞内,进行裂体增植(schizogony)。在红细胞内,除进行裂体增植外,部分裂植子形成配子体,开始有性生植的初期发育。在蚊体内,完成配子生植(gametogony),继而进行孢子增植(sporogony)。
在人体内的发育
分红细胞外期(肝细胞内发育增植)和红细胞内期(红细胞内发育增植及配子体形成)
(1)红细胞外期(exo-erythrocytic cycle,简称红外期):当唾腺中带有成熟子孢子(sporozoite)的雌性按蚊刺吸人血时,子孢子随唾液进入人体,约经30分钟后随血流侵入肝细胞,摄取肝细胞内营养进行发育并裂体增植,形成红细胞外期裂植体。成熟的红细胞外期裂植体内含数以万计的裂植子。裂植子胀破肝细胞后释出,一部分裂植子被巨噬细胞吞噬,其余部分侵入红细胞,开始红细胞内期的发育。间日疟原虫完成红细胞外期的时间约8天,恶性疟原虫约6天,三日疟原虫为11~12天,卵形疟原虫为9天。
一般认为间日疟原虫和卵形疟原虫的子孢子具有遗传学上不同的两种类型,即速发型子孢子(tachysporozoites,TS)和迟发型子孢子(bradysporozoites,BS)。当子孢子进入肝细胞后,速发型子孢子继续发育完成红细胞外期的裂体增植,而迟发型子孢子视虫株的不同,需经过一段或长或短(数月至年余)的休眠期后,才完成红细胞外期的裂体增植。经休眠期的子孢子被称之为休眠子(hypnozoite)。恶性疟原虫和三日疟原虫无休眠子。
美国NovaBios疟原虫检测试剂 疟原虫抗原检测试剂盒
Life history
Parasitic in the body of the four kinds of malaria parasite life history is basically the same, the need for human and Anopheles two hosts. In the human body has been parasitic in the liver cells and red blood cells, the crack propagation (schizogony). In the red blood cells, in addition to crack propagation, part of the merozoites formed gametophyte, began to sexual reproduction of the initial development. In the mosquitoes, gametogony is completed, followed by sporogony.
In the human body development
Erythrocyte extracellular (hepatocyte developmental and proliferative) and erythrocyte internal (erythrocyte developmental proliferation and gametophyte formation)
(1) exo-erythrocytic cycle (exo-erythrocytic cycle): When the salivary glands with mature sporozoites (sporozoite) female Anopheles stabbed human blood, the spores with saliva into the body, about 30 minutes Followed by blood flow into the liver cells, the intake of liver cells within the development of the proliferation of molecules, the formation of red blood cells outside the schizont. Mature red blood cells outside the schizophrenia contains tens of thousands of merozoites. Merozoites burst after the release of liver cells, part of the merozoites are phagocytosis of macrophages, the rest part of the invasion of red blood cells, began the development of red blood cells. Plasmodium falciparum to complete the red blood cell outside the time of about 8 days, about 6 days of Plasmodium falciparum, Plasmodium falciparum for 11 to 12 days, 9 days for the oviposia.
It is generally believed that the sporozoites of Plasmodium vivax and Plasmodium falciparum have two different genetically different types, namely tachysporozoites (TS) and delayed sporozoites (BS). When the sporozoite into the liver cells, the rapid development of sporozoites continue to develop red blood cell outside the crack propagation, and delayed sporozoites of different strains, need to go through a long or short (months to years) of dormancy After the completion of red blood cell outside the crack propagation. The sporozoites of dormancy are called hypnozoites. Plasmodium falciparum and Plasmodium falciparum.
美国NovaBios疟原虫检测试剂 疟原虫抗原检测试剂盒
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【公司名称】 广州健仑生物科技有限公司
【市场部】 杨永汉
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【腾讯 】 2042552662
【公司地址】 广州清华科技园创新基地番禺石楼镇创启路63号二期2幢101-103室