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我们提供的抗体用于实验研究,而不用于诊临床断或治疗程序。
精氨酸tRNA的蛋白转移酶1抗体Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
英文名称 Anti-ATE1
中文名称 精氨酸tRNA的蛋白转移酶1抗体
别 名 Arginine tRNA protein transferase 1; Arginyl-tRNA--protein transferase 1; Arginyl-tRNA-protein transferase; Arginyltransferase 1; R transferase 1; EC 2.3.2.8; AI225793; ATE1_HUMAN.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep
产品类型 一抗
研究领域 细胞生物 免疫学 转录调节因子
蛋白分子量 predicted molecular weight: 59kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human ATE1
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 ATE1, also known as arginyltransferase 1, is an enzyme that is involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. There are two named isoforms.
Function : Involved in the post-translational conjugation ofarginine to the N-terminal aspartate or glutamate of a protein.This arginylation is required for degradation of the protein viathe ubiquitin pathway. Does not arginylate cysteine residues (Bysimilarity).
Isoform ATE1-2: Cytoplasm (By similarity).
Post-translational modifications : Phosphorylated upon DNA damage, probably by ATM or ATR.
Similarity : Belongs to the R-transferase family.
Database links : UniProtKB/Swiss-Prot: O95260.2
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