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我们提供的抗体用于实验研究,而不用于诊临床断或治疗程序。
膜粘连蛋白 I抗体Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
英文名称 Anti-Annexin I
中文名称 膜粘连蛋白 I抗体
别 名 Annexin I; AnnexinI; Annexin I (lipocortin I); Annexin 1; Annexin-1; Annexin1; AnnexinA1; Annexin A1; AnnexinI; ANX 1; ANX A1; ANX1; ANXA 1; ANXA1; ANXA1 protein; Calpactin 2; Calpactin II; CalpactinII; Chromobindin 9; Chromobindin9; HGNC:533; Lipocortin 1; Lipocortin I; ANXA1_HUMAN; Chromobindin-9; Lipocortin 1; Lipocortin I; Lipocortin1; LipocortinI; Lipocortin1; LipocortinI; LPC 1; LPC1; p35; Phospholipase A2 inhibitory protein.
浓 度 1mg/1ml
规 格 0.1ml/100μg 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse
产品类型 一抗
研究领域 细胞生物 细胞骨架
蛋白分子量 predicted molecular weight: 39kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human Annexin I C-terminus
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 This gene encodes a protein that belongs to a family of Ca(2+) dependent phospholipid binding proteins which have a molecular weight of approximay 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti inflammatory activity.
Function : Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity.
Subunit : Homodimer in placenta (20%); linked by transglutamylation. Interacts with DYSF (By similarity).
Subcellular Location : Nucleus (By similarity). Cytoplasm (By similarity). Cell projection, cilium (By similarity). Basolateral cell membrane (By similarity). Note=Found in the cilium, nucleus and basolateral cell membrane of ciliated cells in the tracheal endothelium (By similarity). Found in the cytoplasm of type II pneumocytes and alveolar macrophages (By similarity).
Post-translational modifications : Phosphorylated by protein kinase C, epidermal growth factor receptor/kinase and TRPM7. Phosphorylation results in loss of the inhibitory activity.
Similarity : Belongs to the annexin family.
Contains 4 annexin repeats.
Database links : UniProtKB/Swiss-Prot: P04083.2
Annexin 1是一种分子量为35~36KD的Ca2+依赖性磷脂结合蛋白,能与PS高亲和力特异性结合。
A31286 HTSMC miRNA 人气管平滑肌细胞微小RNA 1 µg 2 µg 5 µg
A31287 HSkMC miRNA 人骨骼肌细胞微小RNA 1 µg 2 µg 5 µg
A31288 HSkMSC miRNA 人骨骼肌卫星细胞微小RNA 1 µg 2 µg 5 µg
A31289 HSkMM miRNA 人骨骼肌成肌细胞微小RNA 1 µg 2 µg 5 µg
A31290 HRGEC miRNA 人肾小球内皮细胞微小RNA 1 µg 2 µg 5 µg
A31291 HRPTEpiC miRNA 人肾近曲小管上皮细胞微小RNA 1 µg 2 µg 5 µg
A31292 HRCEpiC miRNA 人肾皮质上皮细胞微小RNA 1 µg 2 µg 5 µg
A31293 HREpiC miRNA 人肾上皮细胞微小RNA 1 µg 2 µg 5 µg
A31294 HRMC miRNA 人肾系膜细胞微小RNA 1 µg 2 µg 5 µg
A31295 HBdSMC miRNA 人膀胱平滑肌细胞微小RNA 1 µg 2 µg 5 µg
A31296 HUC miRNA 人尿道上皮细胞微小RNA 1 µg 2 µg 5 µg
A31297 HBdSF miRNA 人膀胱基质成纤维细胞微小RNA 1 µg 2 µg 5 µg
A31298 HPEpiC miRNA 人前列腺上皮细胞微小RNA 1 µg 2 µg 5 µg
A31299 HPrF miRNA 人前列腺成纤维细胞微小RNA 1 µg 2 µg 5 µg
A31300 HPSMC miRNA 人前列腺平滑肌细胞微小RNA 1 µg 2 µg 5 µg
A31301 HCO miRNA 人颅骨造骨细胞微小RNA 1 µg 2 µg 5 µg
A31302 HS miRNA 人滑膜细胞微小RNA 1 µg 2 µg 5 µg
A31303 HNPC miRNA 人髓核细胞微小RNA 1 µg 2 µg 5 µg
A31304 HHSEC miRNA 人肝窦内皮细胞微小RNA 1 µg 2 µg 5 µg
A31305 HIBEpiC miRNA 人肝内胆管上皮细胞微小RNA 1 µg 2 µg 5 µg
A31306 HH miRNA 人肝细胞微小RNA 1 µg 2 µg 5 µg
A31307 HHSteC miRNA 人肝星形细胞微小RNA 1 µg 2 µg 5 µg
A31308 HCMEC miRNA 人心脏微血管内皮细胞微小RNA 1 µg 2 µg 5 µg
A31309 HAEC miRNA 人主动脉内皮细胞微小RNA 1 µg 2 µg 5 µg
A31310 HASMC miRNA 人主动脉平滑肌细胞微小RNA 1 µg 2 µg 5 µg
A31311 HCM miRNA 人心肌细胞微小RNA 1 µg 2 µg 5 µg
A31312 HCM-a miRNA 人心肌细胞-成人微小RNA 1 µg 2 µg 5 µg
A31313 HCF miRNA 人心肝成纤维细胞微小RNA 1 µg 2 µg 5 µg
A31314 HCF-av miRNA 人心脏成纤维细胞-成人心室微小RNA 1 µg 2 µg 5 µg
A31315 HCF-aa miRNA 人心肌成纤维细胞-成人心房微小RNA 1 µg 2 µg 5 µg
A31316 HCEpiC miRNA 人角膜上皮细胞微小RNA 1 µg 2 µg 5 µg
A31317 HK miRNA 人角膜细胞微小RNA 1 µg 2 µg 5 µg
A31318 HRPEpiC miRNA 人视网膜色素上皮细胞微小RNA 1 µg 2 µg 5 µg
A31319 HLEpiC miRNA 人晶状体上皮细胞微小RNA 1 µg 2 µg 5 µg
A31320 HIPEpiC miRNA 人虹膜色素上皮细胞微小RNA 1 µg 2 µg 5 µg
A31321 HConF miRNA 人结膜成纤维细胞微小RNA 1 µg 2 µg 5 µg
A31322 HNPCEpiC miRNA 人无色素睫状上皮细胞微小RNA 1 µg 2 µg 5 µg
A31323 HTMC miRNA 人小梁网细胞微小RNA 1 µg 2 µg 5 µg
A31324 HAmEpiC miRNA 人羊膜上皮细胞微小RNA 1 µg 2 µg 5 µg
A31325 HVT miRNA 人滋养层绒毛细胞微小RNA 1 µg 2 µg 5 µg
A31326 HVMF miRNA 人绒毛间叶成纤维细胞微小RNA 1 µg 2 µg 5 µg
A31327 HPA-v miRNA 人前脂肪细胞-内脏微小RNA 1 µg 2 µg 5 µg
A31328 HPA-s miRNA 人前脂肪细胞-皮下微小RNA 1 µg 2 µg 5 µg
A31329 HMSC-bm miRNA 人间充质干细胞-骨髓微小RNA 1 µg 2 µg 5 µg
A31330 HMSC-ad miRNA 人间充质干细胞-脂肪微小RNA 1 µg 2 µg 5 µg
A31331 HMSC-hp miRNA 人间充质干细胞-肝脏微小RNA 1 µg 2 µg 5 µg
A31332 HUMSC miRNA 人脐带间充质干细胞微小RNA 1 µg 2 µg 5 µg
A31333 HPMSC miRNA 人肺间充质干细胞微小RNA 1 µg 2 µg 5 µg
A31334 HMEpiC miRNA 人乳腺上皮细胞微小RNA 1 µg 2 µg 5 µg
A31335 HMF miRNA 人乳腺成纤维细胞微小RNA 1 µg 2 µg 5 µg
A31336 HUVEC miRNA 人脐静脉内皮细胞微小RNA 1 µg 2 µg 5 µg
A31337 HUAEC miRNA 人脐动脉内皮细胞微小RNA 1 µg 2 µg 5 µg
A31338 HUVSMC miRNA 人脐静脉平滑肌细胞微小RNA 1 µg 2 µg 5 µg
A31339 HUASMC miRNA 人脐动脉平滑肌细胞微小RNA 1 µg 2 µg 5 µg
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